710 Regulatory T cells impair cutaneous wound healing in diabetic mice
نویسندگان
چکیده
منابع مشابه
Synergistic Effect Of Treadmill Exercise And Green Tea Extract On Cutaneous wound Healing In Diabetic Mice
Aim and Background: In the study , synergistic effect of green tea (camellia sinesis) extract and treadmill aerobic exercise on wound healing in streptozotocin induced diabetic mice has been investigated. Material and methods: The number of 50 male mice with the approximately weight of 30-35 gram health and adult are put in 5 groups: non diabetic – immobile , diabetic - immobile, diabetic...
متن کاملClinically relevant doses of lidocaine and bupivacaine do not impair cutaneous wound healing in mice.
BACKGROUND Lidocaine and bupivacaine are commonly infiltrated into surgical cutaneous wounds to provide local anaesthesia after surgical procedures. However, very little is known about their effects on cutaneous wound healing. If an inhibitory effect is demonstrated, then the balance between the benefits of postoperative local anaesthesia and the negatives of impaired cutaneous wound healing ma...
متن کاملSkin-derived precursor cells promote wound healing in diabetic mice.
BACKGROUND Impaired wound healing as one of the complications arising from diabetes mellitus is a serious clinical issue. Recently, various cell therapies have been reported for promotion of wound healing. Skin-derived precursor cells (SKPs) are multipotent adult stem cells with the tendency to differentiate into neurons. We investigated the potency of promoting diabetic wound healing by the ap...
متن کاملMast Cells in Cutaneous Wound Healing
Mast cells are suggested to participate in wound healing, but their specific role has remained obscure. Mast cells are a rich source of inflammatory mediators, such as histamine, proteoglycans, the proteases tryptase and chymase, lipids, growth factors and cytokines. Among these mediators, there are many that have effects on cell growth, tissue turnover and repair. The aim of this study was to ...
متن کاملRegulatory roles of androgens in cutaneous wound healing.
Although the effects of androgens on wound healing are poorly characterised, the androgen receptor is expressed by inflammatory cells, keratinocytes and fibroblasts during wound healing, suggesting that androgens may regulate inflammatory and/or repair processes. In fact, it appears that endogenous testosterone inhibits wound healing and promotes inflammation since castration of male mice or sy...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2016
ISSN: 0022-202X
DOI: 10.1016/j.jid.2016.02.753